Chronic kidney disease halt

Chronic kidney disease, also called chronic renal insufficiency, is the most common medical problem and one of the leading causes of death in older cats. More than a third of all over eight year old cats suffer from it. As the disease develops slowly, symptoms and elevated blood levels of the kidney do not become apparent until more than 70 percent of kidney tissue has been damaged. So it was with the ten year old tomcat Teddy. When Teddy was vaccinated at the Chronic Kidney Disease six months ago, he was a strong and, as the vet's assistant confirms, a very resilient cat. Now, half a year later, Teddy is no longer recognizable: From the vigorous, combative hangover has become in a half a year a lanky, apathetic animal. At the veterinarian's request, Teddy's owner tells her that the cat has been drinking a lot lately, but has little appetite and is lazy most of the time. He also suffers from diarrhea and frequent vomiting. During the examination, the vet determines that Teddy is dehydrated, that his kidney levels and phosphate levels in the blood are greatly increased, and that Teddy excretes protein with the urine. The findings speak for the typical chronic kidney disease of older cats.

Kidneys have important tasks

The kidneys produce urine by filtering out excess blood and depleting substances from the blood. The filtering process takes place in many tiny functional units of the kidney called nephrons. The entire kidney function consists of the activity of the individual nephrons. In the event of damage that destroys intact nephrons, the kidney is initially able to continue its task undisturbed, as the remaining nephrons may increase their capacity to sustain kidney function over a period of time. The increase in capacity, however, is due to a pressure increase in the kidney, which not only destroys other functional units, but also leads to increased blood pressure, which in turn has negative effects on the heart, eyes and brain. However, the kidney also fulfills important tasks in the regulation of the mineral balance (sodium, potassium, calcium and phosphate). The more nephrons are destroyed, the less the kidney can fulfill its function. It loses the ability to eliminate waste products from the metabolism through the urine, which is why they accumulate in the blood and poison it. Conversely, however, it comes to the pathological excretion of protein with the urine, which is why the animals lose weight. But that is not all, the increased protein excretion also causes a chronic inflammation in the nephron, which has the pathological conversion of kidney tissue into functionless connective tissue. This is called fibrosis of the kidney. As too much water migrates into the urine, the animals dry out. Both the fluid balance and the mineral distribution and the acid-base balance of the organism get out of balance.

Elevated blood pressure as an indication of kidney damage

Since only regular check-ups allow early support and relief of the kidney, the blood pressure of cats and dogs should be checked at each vet visit. Increased blood pressure is often the first indication of kidney damage, as blood pressure is usually elevated before any changes in kidney levels are seen in the laboratory. Only when the chronic kidney disease is already well advanced, the blood test shows increased urea and creatinine levels and too high phosphate levels - all waste products of the protein metabolism.

Calcification of kidney tissue due to high phosphate levels

Cats as strict carnivores are exposed to a particularly high intake of phosphates, as meat is naturally rich in phosphate. Compared with the normal diet of a human take cats with the commercial cat food, or even self-prepared meat diet in the ratio about six times more dietary phosphate. This remains together with urea as a waste product of protein metabolism in the blood and must be eliminated via the kidney with the urine. However, if an animal suffers from Chronic Kidney Disease, the kidney loses the ability to eliminate waste products, as mentioned above. Sick kidneys work like an upside-down filter: too much water migrates into the urine, too much waste, including phosphate, remains in the blood. While high urea levels in the blood cause fatigue, apathy and vomiting, increased phosphate levels lead to the release of calcium from the bones. The result is a calcification of kidney tissue and thus further damage to the kidney.

Support the kidneys in time with Pronefra

Findings that indicate the chronic kidney disease (Chronic Kidney Disease), must be taken very seriously, because already damaged kidney tissue can not regenerate. Without therapy, the course of the disease is progressive and incurable, the transition to uremia (urine poisoning) fluent. The animals then suffer from cramps, tremors, itching and epileptic seizures. Finally, they fall into the uremic coma and go to miserable ground. To prevent this, it is very important to intervene early and to stop the progression of the chronic kidney disease as long as possible. This is now possible with the new food supplement Pronefra. This tasty suspension may delay or even prevent the progression of clinical symptoms. This results in an improved quality of life for the animal and a longer life expectancy. The success of Pronefra is based on the interaction of five ingredients with four-fold positive effects: 1.) Two different phosphate binders, namely calcium carbonate and magnesium carbonate, bind phosphorus from the food already in the intestine, so that it is not absorbed into the blood, but excreted in the feces. The resulting phosphate reduction in the blood has a positive effect on kidney function. 2.) Chitosan relieves the kidneys by detoxifying the body by binding urinary toxins and breakdown products in the gastrointestinal tract and also eliminates them with the feces. 3.) Plant polysaccharides from the butterfly plant "Astragalus membranaceus" maintain the normal kidney architecture by blocking the chronic inflammation of the kidney and thus preventing the fibrosis, ie conversion of the kidney tissue into functionless connective tissue. Astragalus is also used in traditional Chinese medicine as an important medicinal plant in kidney disease and is now for the first time part of a modern means of supporting kidney function. 4.) Vascular active oligopeptides from marine fish help to prevent harmful high blood pressure.

Easy administration and good acceptance of the product

Pronefra is in liquid form as a suspension and is so tasty that it is also very welcome by sensitive animals. This is important because kidney patients usually suffer from bad appetite. For easy dosing, the package comes with a dosing syringe. Pronefra can be administered either with the feed or directly into the oral cavity.